Amber Rx-only estradiol tablet bottle and compounded progesterone capsule bottle, labeled by a state-licensed pharmacy, with blush and teal glass petals. Program · 2 treatments

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Women's Hormone Program

Estradiol + progesterone

Menopause hormone therapy for women with a uterus: estradiol for hot flashes and night sweats, with progesterone to protect the uterine lining.

Includes
Estradiol tablet + progesterone capsule
Form
Two daily pills
Before starting
Video visit and labs ($89.50 HRT panel, paid to the lab)
Filled by
State-licensed pharmacy

Choose your plan

Separately $148 · program saves $49/mo

No charge unless a provider approves · Start assessment

What's included

All 2 treatments, prescribed and managed together.

Provider careProvider messagingDiscreet packaging12-month price lock

Why they work together

Estradiol treats hot flashes and night sweats by replacing some of the estrogen your body stops making. On its own, estrogen can thicken the lining of the uterus.

Progesterone balances that effect, which is why women who still have a uterus take both.

Program vs. separately

Same medications, same provider care, on one plan.

 Women's Hormone ProgramBuying separately
Price per month (quarterly)$139$148
MedicationsEstradiol + ProgesteroneEstradiol + Progesterone
Provider careOne provider manages all of itIncluded with each
ShipmentsOne plan, one refill scheduleSeparate refills

What to expect

Everyone responds differently. Your provider checks in and adjusts your plan along the way.

Weeks 1–4

Many women notice fewer or milder hot flashes within a few weeks.

Months 1–3

Spotting or changes in bleeding can happen as your body adjusts. Your provider may adjust doses.

Ongoing

A yearly review of whether to continue, plus routine screenings like mammograms.

Is it right for you?

Your provider reviews each medication separately before prescribing.

Often a good fit

  • Hot flashes or night sweats from menopause
  • Still have a uterus
  • Under 60 or within about 10 years of menopause

Usually not a fit

  • Breast cancer or another estrogen-sensitive cancer
  • History of blood clots, stroke, or heart attack
  • Unexplained vaginal bleeding
  • Liver disease
  • Peanut allergy (progesterone capsules contain peanut oil)

Not a complete list. Tell your provider about all health conditions and medications.

Possible side effects

Most side effects are mild. Your care team is a message away if something doesn't feel right.

Estradiol

Breast tendernessBloatingHeadacheNauseaSpotting

Progesterone

DrowsinessDizzinessBreast tendernessHeadacheBloatingMood changes

Get medical help right away for

  • Unusual vaginal bleeding
  • Chest pain, shortness of breath, or pain and swelling in a leg
  • Sudden severe headache, vision changes, or trouble speaking
  • A new breast lump

For a medical emergency, call 911.

How to take it

Always follow the directions on your labels and from your provider.

Estradiol daily

Take your estradiol tablet at the same time each day.

Progesterone at bedtime

Take your progesterone capsule right before bed. It can cause drowsiness.

Keep up with screenings

Stay current on mammograms and your yearly review.

Program questions

What if I’ve had a hysterectomy?

You likely don’t need progesterone. Ask your provider about estradiol on its own.

What if my provider only prescribes one medication?

Then you'll pay that medication's single-treatment price instead of the program price.

How long can I stay on hormone therapy?

There is no single cutoff. You and your provider review the benefits and risks at least once a year.

Can I cancel?

Yes. Cancel any time before your next billing date and you will not be charged again. Anything you have already paid for still ships.

Prefer a single treatment?

See all Hormone Health treatments

Start the Women's Hormone Program.

Answer a few questions and a licensed provider will review each medication for you.

Program

Important safety information

Last updated

Estradiol: Estrogen therapy increases the risk of endometrial cancer in women with a uterus who do not also take a progestogen. Estrogen, alone or with progestins, may increase the risk of heart attack, stroke, blood clots, breast cancer, and probable dementia. Use the lowest effective dose for your goals, and review treatment with your provider regularly. Report unusual vaginal bleeding right away.

Progesterone: Do not take progesterone capsules if you are allergic to peanuts. Estrogens with progestins may increase the risk of heart attack, stroke, blood clots, breast cancer, and probable dementia. Progesterone can cause drowsiness and dizziness; use caution driving or operating machinery. Report unusual vaginal bleeding right away.

Compounded medication, prepared by a state-licensed pharmacy for individual patients. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Prescribed only if your provider determines it is clinically appropriate for you.

This is not a complete list of risks. Talk with your provider and read the full prescribing information or medication guide for each medication.