Amber Rx-only Biest capsule bottle, labeled as dispensed by a state-licensed pharmacy, with peach capsules before aqua and blush glass ovals. Prescription only

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Biest Capsule

Prescription onlyPrescription required

Estriol and estradiol. Prescribed after a provider review.

Hormone Health

Compounded bioidentical estrogen, taken daily.

Form
Oral capsule, daily
Labs
Required; $89.50 HRT panel, paid to the lab
Prescribed for
Female
PricingFrom $109/mo
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Quick answer

Biest Capsule at a glance

Biest is a blend of two bioidentical estrogens: 20% estradiol and 80% estriol.

How it’s taken: oral capsule, daily.

Bloodwork is required before and during treatment.

A prescription from a licensed provider is required.

Updated

How Biest Capsule works

Biest is a blend of two bioidentical estrogens: 20% estradiol and 80% estriol.

Estradiol is the more potent estrogen that relieves hot flashes and protects bones.

Estriol is a gentler estrogen that's considered safer for long-term use.

Together they provide effective menopause symptom relief with a more balanced hormonal profile than estradiol alone.

Bioidentical means it's chemically identical to the estrogen your body naturally makes.

What Biest is

A compounded bioidentical preparation. FDA has raised concerns specifically about marketing compounded hormone preparations as safer or more natural than approved products. We do not make that claim, and you should be sceptical of anyone who does.

Two estrogens, in a set ratio

Estriol and estradiol combined. Because it is compounded rather than a fixed commercial product, your provider can set the ratio.

Estriol has no approved product

Estriol is not a component of any FDA-approved drug in the United States.

Not FDA-approved

Compounded Biest is not an FDA-approved drug product and FDA does not review it for safety, effectiveness or quality.

Prescribed with monitoring

Your provider decides the ratio, the strength and what monitoring goes alongside it.

Biest Capsule questions

Is this safer than conventional HRT?

We will not tell you it is safer. "Bioidentical" describes molecular structure — the molecule is structurally identical to the one your body makes — and it is not a statement about safety or effectiveness. Compounded preparations are not FDA-approved drug products, and FDA has raised specific concerns about compounded hormone therapy being marketed as a safer or more natural alternative to approved products. Your provider will go through the actual risks and benefits with you.

See if Biest Capsule is right for you.

Answer a few questions and a licensed provider will review your options.

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Prescription only

Important safety information

Last updated

Testosterone is a Schedule III controlled substance.

Prescribing it is subject to DEA telemedicine rules and state controlled-substance requirements in addition to ordinary standards of care.

Compounded hormone preparations, including compounded testosterone, Biest, progesterone and thyroid preparations, are not FDA-approved drug products.

Estriol is not a component of any FDA-approved drug.

Testosterone therapy requires baseline and ongoing laboratory monitoring.

Your provider determines what testing is required and when.

Reported risks include erythrocytosis, effects on fertility and spermatogenesis, worsening of sleep apnoea, acne, and cardiovascular considerations your provider will review against your history.

Not appropriate in pregnancy, in anyone who is or may become pregnant, or where a provider identifies a contraindication such as active prostate or breast malignancy.

FDA has raised concerns specifically about marketing compounded hormone preparations as safer or more natural than approved products.

We do not make that claim and you should be sceptical of anyone who does.

Compounded medication, prepared by a state-licensed pharmacy for individual patients. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Prescribed only if your provider determines it is clinically appropriate for you.

This is not a complete list of risks. Talk with your provider and read the full prescribing information or medication guide.

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