Amber Rx-only compounded enclomiphene capsule bottle, labeled as prepared by a state-licensed pharmacy, with pale-teal capsules and a teal glass spiral.

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Enclomiphene

CompoundedPrescription required

Help your body make its own testosterone. Daily capsule.

  • Sperm counts preserved in studies
  • Labs first
  • Pharmacy on your label

Compounded enclomiphene, prepared by a state-licensed pharmacy

Enclomiphene signals your brain to tell your body to make more of its own testosterone. Unlike TRT, it doesn't shut down natural sperm production.

Form
Capsule
How often
Daily
Before starting
Labs ($88.25 TRT panel, paid to the lab) and a video visit
Made by
State-licensed compounding pharmacy

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Quick answer

Enclomiphene at a glance

Enclomiphene signals your brain to tell your body to make more of its own testosterone.

How it’s taken: capsule, daily.

It starts at $119/mo at Surna, with provider care included.

A prescription from a licensed provider is required. It’s compounded by a state-licensed pharmacy and is not FDA-approved.

Compare: TRT vs. enclomiphene

Updated

How Enclomiphene works

Your pituitary gland releases hormones called LH and FSH, which tell the testes to make testosterone and sperm. Enclomiphene blocks estrogen’s feedback signal in the brain, so the pituitary sends a stronger signal.

Because your own body is making the testosterone, sperm production is generally preserved.

What to expect

Everyone responds differently. Your provider checks in and adjusts your plan along the way.

Before you start

Labs and a video visit confirm low testosterone and a working pituitary signal.

Weeks 4–6

Follow-up labs check your testosterone and estrogen levels.

Ongoing

Your provider adjusts your dose based on your labs and how you feel.

Is it right for you?

Your provider makes the final call after reviewing your health history and labs.

Often a good fit

  • Men with low testosterone who want to preserve fertility
  • Prefer a daily capsule over injections
  • Normal pituitary function, confirmed with labs

Usually not a fit

  • Testes that don’t respond to hormone signals (primary testicular failure)
  • History of blood clots
  • Liver disease
  • Uncontrolled thyroid or adrenal problems

Not a complete list. Tell your provider about all health conditions and medications.

Possible side effects

Most side effects are mild. Your care team is a message away if something doesn't feel right.

More common

HeadacheHot flashesNauseaMood changes

Get medical help right away for

  • Blurry vision or other vision changes
  • Pain or swelling in one leg
  • Chest pain or shortness of breath

For a medical emergency, call 911.

How to take it

Always follow the directions on your label and from your provider.

Take it daily

Take one capsule at the same time each day, or as your provider directs.

Keep up with labs

Follow-up bloodwork helps your provider fine-tune your dose.

Report vision changes

Stop and contact your care team right away if your vision changes.

Enclomiphene questions

Enclomiphene or TRT?

TRT replaces testosterone directly and can lower sperm count. Enclomiphene helps your body make its own. If fertility matters to you, it's often the first option to discuss.

Is it the same as Clomid®?

Clomid® (clomiphene) contains two forms, enclomiphene and zuclomiphene. Enclomiphene is the form that raises testosterone, while zuclomiphene stays in the body longer.

Is enclomiphene FDA-approved?

No. It is compounded by a state-licensed pharmacy. Compounded medications are not FDA-approved or reviewed by the FDA for safety, effectiveness, or quality.

See if Enclomiphene is right for you.

Answer a few questions and a licensed provider will review your options.

Compounded

Important safety information

Last updated

Enclomiphene can cause headache, hot flashes, nausea, and mood changes. Stop taking it and contact your provider right away if you notice vision changes. Tell your provider about any history of blood clots, liver disease, or thyroid or adrenal problems. Clomid® is a registered trademark of its owner.

Compounded medication, prepared by a state-licensed pharmacy for individual patients. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Prescribed only if your provider determines it is clinically appropriate for you.

This is not a complete list of risks. Talk with your provider and read the full prescribing information or medication guide.