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Sermorelin
A peptide that signals the body to release growth hormone. Shot or lozenge.
- Taken at bedtime
- Labs may be required
- Pharmacy on your label
Compounded growth hormone–releasing peptide · injection or lozenge
Sermorelin signals your pituitary gland to release more of your own growth hormone, in your body’s natural rhythm. Individual results vary.
- Form
- Injection or lozenge
- How often
- Nightly, before bed
- Labs
- May be required
- Made by
- State-licensed compounding pharmacy
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No charge unless a provider approves · Start assessment
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Quick answer
Sermorelin at a glance
Sermorelin signals your pituitary gland to release more of your own growth hormone, in your body’s natural rhythm.
How it’s taken: injection or lozenge, nightly, before bed.
It starts at $119/mo at Surna, with provider care included.
A prescription from a licensed provider is required. It’s compounded by a state-licensed pharmacy and is not FDA-approved.
Updated
How Sermorelin works
Growth hormone naturally declines with age. Instead of replacing it directly, sermorelin mimics GHRH, the hormone that tells your pituitary gland when to release growth hormone.
Taken at bedtime, it lines up with the natural growth hormone release that happens during deep sleep.
What to expect
Everyone responds differently. Your provider checks in and adjusts your plan along the way.
Weeks 1–4
Nightly injections. Changes are gradual, and some people notice sleep changes first.
Months 2–3
Your provider may check labs like IGF-1 and adjust your dose.
Ongoing
Regular check-ins to see how it fits your goals.
Is it right for you?
Your provider makes the final call after reviewing your health history and labs.
Often a good fit
- Adults looking to support sleep and recovery
- People who prefer supporting natural hormone production over replacement
- Willing to do labs if your provider asks
Usually not a fit
- Active cancer or a history of certain cancers
- Pregnant or breastfeeding
- Untreated thyroid problems
Not a complete list. Tell your provider about all health conditions and medications.
Possible side effects
Most side effects are mild. Your care team is a message away if something doesn't feel right.
More common
Get medical help right away for
- Signs of an allergic reaction, like hives, swelling of your face or throat, or trouble breathing
For a medical emergency, call 911.
How to take it
Always follow the directions on your label and from your provider.
Injection: at bedtime
Inject under the skin of your belly or thigh before bed, rotating spots each night.
Lozenge: let it dissolve
Place it between your cheek and gum at bedtime and let it dissolve fully. Don’t chew it.
Store it properly
Follow the storage and mixing directions on your label.
Sermorelin questions
Injection or lozenge?
Injections are absorbed more predictably. The lozenge avoids needles. Your provider can help you choose based on your goals and preferences.
Is sermorelin the same as HGH?
No. HGH replaces growth hormone directly. Sermorelin prompts your body to release its own, which keeps your natural feedback system in place.
Is sermorelin FDA-approved?
A brand-name version was once FDA-approved but is no longer sold in the U.S. The sermorelin we prescribe is compounded by a state-licensed pharmacy and is not FDA-approved or reviewed by the FDA for safety, effectiveness, or quality.
Related treatments
See if Sermorelin is right for you.
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Important safety information
Last updated
Sermorelin can cause injection site reactions, flushing, headache, and dizziness. Tell your provider about any history of cancer, thyroid problems, pregnancy, or breastfeeding. Seek emergency care for signs of a serious allergic reaction.
Compounded medication, prepared by a state-licensed pharmacy for individual patients. Compounded drugs are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Prescribed only if your provider determines it is clinically appropriate for you.
This is not a complete list of risks. Talk with your provider and read the full prescribing information or medication guide.